BLOCKING CONNEXIN 43 AND ITS PROMOTION OF ATP RELEASE FROM RENAL TUBULAR EPITHELIAL CELLS AMELIORATES RENAL FIBROSIS

Blocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis

Abstract Whether metabolites derived from injured renal tubular epithelial cells (TECs) participate in renal fibrosis is poorly explored.After TEC injury, various metabolites are released and among the most potent is adenosine triphosphate (ATP), which is released via ATP-permeable channels.In these hemichannels, connexin 43 (Cx43) is the most comm

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Analysis of international experience in the legal regulation of posthumous consent for donation and its implementation in Ukraine

The relevance of this study is associated with the acute shortage of organs for transplantation, which is a widespread issue in healthcare systems worldwide.The purpose of the study is to identify potential ways to increase the number of individuals providing posthumous consent for donation and, consequently, the availability of donor material in U

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Ligamentous instability of the first ray: A case report introducing the naviculocuneiform kissing sign on MRI scan

Acute instability of the first ray following trauma is a rare type of Lisfranc injury.Plain radiographs may demonstrate instability if there is a clear dislocation of the first ray, however subtle injuries are difficult to recognise.Magnetic resonance imaging (MRI) has been described in the literature as an adjunct in the diagnosis of subtle Lisfra

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